Mammalian genes involved in viral infection and tumor...

Details Mammalian genes involved in viral infection and tumor... Mammalian genes involved in viral infection and tumor...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2305312

The present invention provides methods of identifying cellular genes necessary for viral growth and cellular genes that function as tumor suppressors. Thus, the present invention provides nucleic acids related to and methods of reducing or preventing viral infection or cancer. The invention also provides methods of producing substantially virus- free cell cultures and methods for screening for additional such genes.

L'invention concerne des procédés permettant d'identifier des gènes cellulaires nécessaires à la multiplication des virus et des gènes cellulaires nécessaires à la neutralisation tumorale. L'invention concerne donc des acides nucléiques et des procédés liés à la réduction ou à la prévention de l'infection virale ou du cancer. L'invention concerne également des procédés permettant de fournir des cultures cellulaires sensiblement dépourvues de virus et des procédés relatifs au criblage de gènes additionnels de ce type.

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