Modulation of peroxisome proliferation-activated receptors

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/04 (2006.01) A61K 31/12 (2006.01) A61K 31/165 (2006.01) A61K 31/216 (2006.01) A61K 31/352 (2006.01) A61K 31/381 (2006.01) A61K 31/5575 (2006.01) A61K 31/713 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 29/00 (2006.01) C07K 16/40 (2006.01) C12Q 1/26 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) C12N 15/53 (2006.01)

Patent

CA 2553115

A method of treating a peroxisome proliferators-activated receptors related disease by administering to a subject in need thereof an effective amount of a modulator of 15-keto prostaglandin-.DELTA.13-reductase. Also disclosed are methods of identifying a compound for inhibiting activity of the reductase and of lowering blood glucose levels by administering to a subject an effective amount of a reductase inhibitor.

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