Polypeptides and polynucleotides encoding same

Details Polypeptides and polynucleotides encoding same Polypeptides and polynucleotides encoding same

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/555 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2394917

The invention provides polypeptides, designated herein as NOV polypeptides, as well as polynucleotides encoding NOV polypeptides, and antibodies that immunospecifically-bind to NOV polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the NOV polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.

L'invention concerne des polypeptides désignés polypeptides NOV, ainsi que des polynucléotides codant ces polypeptides NOV, des anticorps se fixant de façon immunospécifique à ce polypeptide NOV ou à ce polynucléotide, ou leurs dérivés, variantes ou mutants ou fragments. Elles concernent, de plus, des procédés, consistant à utiliser le polypeptide NOV, le polynucléotide et l'anticorps de ce dernier afin de détecter, de prévenir et de traiter une variété importante d'états pathologiques.

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