Remedies/preventives for abnormal motions accompanying...

A - Human Necessities – 61 – K

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A61K 31/435 (2006.01) A61K 31/439 (2006.01)

Patent

CA 2274651

Preventives/remedies for abnormal motions accompanying disorders in the extrapyramidal system which contain as the active ingredient (1S)-3-[2-(2- adamantyl)ethyl]-1,8,8-trimethyl-3-azabicyclo[3.2.1]-octane or a pharmacologically acceptable acid-addition salt thereof. These drugs are novel and efficacious preventives/remedies for a disease selected from the group consisting of Parkinson's disease, striatonigral degeneration, olivopontocerebellar atrophy, Shy-Drager syndrome, progressive supranuclear palsy, essential tremor, Huntington's chorea, senile chorea, fastigiobulbar pallidial Luys body atrophy, benign familial chorea, acanthocytic chorea, torsion dystonia, Meige's syndrome, and Segawa disease.

Medicaments pour traiter/prévenir les mouvements anormaux qui accompagnent les troubles du système nerveux extrapyramidal, dont le principe actif est (1S)-3-[2-(2-adamantyl)éthyl]-1,8,8-triméthyl-3-azabicyclo[3.2.1]-octane ou un sel d'addition d'acide pharmaceutiquement acceptable. Ces médicaments d'un type nouveau sont efficaces pour prévenir/traiter toute maladie appartenant au groupe des maladies suivantes: maladie de Parkinson, dégénérescence du système nigro-striatal, atrophie olivo-ponto-cérébelleuse, syndrome de Shy-Drager, paralysie supranucléaire progressive, tremblement essentiel, chorée de Huntington, chorée sénile, atrophie fastigiobulbaire du corps de Luys, chorée familiale bénigne, chorée acanthocytique, dystonie de torsion, syndrome de Meige et maladie de Segawa.

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