Pik4ca as modifier of the rac pathway and methods of use

Details Pik4ca as modifier of the rac pathway and methods of use Pik4ca as modifier of the rac pathway and methods of use

A - Human Necessities

61

K

A61K 38/17 (2006.01)

Patent

CA 2579630

Human PIK4CA genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of PIK4CA are provided.

Des gènes PIK4CA humains sont identifiés comme modulateurs du mécanisme d'action RAC et constituent, de ce fait, des cibles thérapeutiques pour des troubles associés à une fonction RAC . L'invention concerne des procédés d'identification de modulateurs de RAC, procédés comprenant le triage des agents modulant l'activité de PIK4CA.

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