Buccal composition containing s(+) flurbiprofen or ketoprofen

A - Human Necessities – 61 – K

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A61K 31/19 (2006.01) A61K 7/16 (1990.01) A61K 7/18 (1990.01)

Patent

CA 2064722

A composition for the treatment of disorders associated with periodontal disease affecting soft tissue and bone of the oral cavity, and a composition useful in the method. The method comprises applying to buccal membranes a therapeutically effective quantity of at least one S enantiomer, generally an S(+) enantiomer, of a nonsteroidal anti-inflammatory drug, such as S(+) flurbiprofen or S(+) ketoprofen. The composition is a formulation which is a toothpaste or which is a mouthwash.

Composition pour le traitement des affections associées aux maladies périodontales affectant les tissus mous et les os de la cavité orale et composition utile dans cette méthode. La méthode comprend l'application sur les membranes de la cavité bucale d'une quantité suffisante pour avoir un effet thérapeutique d'au moins un énantiomère S, généralement un énantiomère S(+), d'un médicament anti-inflammatoire non-stéroïdien, comme un flurbiprofène S(+) ou un ketoprofène S(+). La composition se présente sous forme de pâte dentifrice ou de liquide pour bains de bouche.

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