C - Chemistry – Metallurgy – 40 – B
Patent
C - Chemistry, Metallurgy
40
B
C40B 40/06 (2006.01) A61K 8/00 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C12N 15/10 (2006.01) C12N 15/11 (2006.01) C12N 15/86 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) C40B 30/00 (2006.01) C40B 30/04 (2006.01)
Patent
CA 2612389
The present invention relates to the selection of a set of SNP markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's longevity, their protection against age-related diseases and/or their response to a particular drug or drugs.
La présente invention se rapporte à la sélection d'un ensemble de marqueurs de polymorphismes d'un seul nucléotide (SNP) destiné être utilisé dans des études d'association portant sur l'ensemble du génome, se fondant sur une cartographie des déséquilibres de liaison. L'invention se rapporte en particulier aux domaines de la pharmacogénomique, des diagnostics, des traitements de patients, et de l'utilisation des données de l'haplotype génétique pour prédire la longévité d'un individu, sa protection contre les maladies liées à l'âge et/ou sa sensibilité à un ou à plusieurs médicaments particuliers.
Allard Rene
Belouchi Abdelmajid
Bradley Walter Edward
Cousineau Johanne
Croteau Pascal
Genizon Biosciences Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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