Methods of preparing and using stem cell compositions and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/10 (2006.01) A61K 35/00 (2006.01)

Patent

CA 2542120

The present invention provides novel stem cell compositions having significant therapeutic and practical advantages, as well as methods of preparing and using such compositions for the treatment and prevention of injury and disease in patients. The invention may be applied to stem cell populations isolated from a wide variety of animals, including humans, and tissues. In particular applications, the invention is used to prepare a stem cell composition from a collagen-based tissue, such as adipose tissue, isolated from a patient, and the stem cell composition is subsequently provided to a site of actual or potential injury in the patient. The invention further includes related kits comprising the stem cell compositions, which are remarkably stable and retain viability and efficacy during storage and shipment.

La présente invention se rapporte à de nouvelles compositions de cellules souches, qui présentent d'importants avantages thérapeutiques et pratiques, ainsi qu'à des procédés de préparation et d'utilisation de telles compositions pour traiter et prévenir des blessures et des maladies chez des patients. La présente invention peut être appliquée à des populations de cellules souches isolées d'une grande variété d'animaux, notamment d'êtres humains, et de tissus. Dans des modes de réalisation particuliers, l'invention permet de préparer une composition de cellules souches issue d'un tissu à base de collagène, tel qu'un tissu adipeux, isolé d'un patient, ladite composition de cellules souches étant ensuite administrée au patient, sur le site d'une blessure réelle ou potentielle. L'invention concerne également des kits associés contenant les compositions de cellules souches selon l'invention, lesquels sont remarquablement stables et conservent leur viabilité et leur efficacité lors de leur stockage et de leur transport.

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