A process for the resolution of nefopam

Details A process for the resolution of nefopam A process for the resolution of nefopam

C - Chemistry, Metallurgy

07

D

C07D 267/00 (2006.01)

Patent

CA 2548507

A process for increasing the optical purity of a mixture of enantiomers of nefopam uses a substantially single enantiomer of a O,O-diaroyltartaric acid as a resolving agent, via a bisnefopam salt of the acid. This salt is new.

L'invention concerne un procédé permettant d'augmenter la pureté optique d'un mélange d'énantiomères de Nefopam. Ce procédé utilise un énantiomère sensiblement unique d'acide O,O-diaroyltartarique comme agent de résolution, par un sel bisnefopam de l'acide. Ce sel est nouveau.

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