Modulating drug release rate by controlling the kinetics of...

Details Modulating drug release rate by controlling the kinetics of... Modulating drug release rate by controlling the kinetics of...

A - Human Necessities

61

K

A61K 9/10 (2006.01)

Patent

CA 2730598

Methods and compositions relate to modulating the release profile of drug molecules from a hydrogel by controlling the kinetics of the pH transition of the hydrogel. The hydrogel is formed by in situ polymerization and includes a drug molecule having a pKa between the pH of the formed hydrogel and the physiologic environment in which the hydrogel is placed.

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