Process for the preparation of o-desmethylvenlafaxine

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 213/08 (2006.01) A61K 31/135 (2006.01) A61P 25/24 (2006.01) C07C 215/64 (2006.01)

Patent

CA 2731165

The present invention provides a convenient and efficient process for the preparation of O-desmethylvenlafaxine (ODV) or a salt thereof, comprising the reaction of venlafaxine, or a salt thereof, with a thiourea or a mixture of thioureas.

La présente invention concerne un procédé commode et efficace d'élaboration d'O-desméthylvenlafaxine (ODV) ou de l'un de ses sels, consistant en une réaction de venlafaxine ou de l'un de ses sels, avec une thio-urée ou un mélange de thio-urées.

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