Development of natural killer cells and functional natural...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/0783 (2010.01) A61K 35/12 (2006.01) A61K 35/14 (2006.01) A61K 39/395 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2519535

The invention relates to natural killer cells and methods for the development of immortalized natural killer cells and use of the natural killer cells. A growth and culture system is described that supports increased natural killer cell development, and provides for the establishment of continuous natural killer cell lines. Additionally, the disclosed method for generating natural killer cells may be used to produce large numbers of natural killer cells for therapeutic applications and for natural killer cell research.

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