Antitumour agents

Details Antitumour agents Antitumour agents

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2150711

Novel mitosenes useful as antitumour agents are compounds of formula (II) in which R1 and R2 together with the nitrogen to which they are attached represent a cyclic or acylic secondary amine, R3 is hydrogen or an alkyl group, R4 and R5 are each independently hydrogen or an alkyl group and Z is a leaving group, or a salt thereof.

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