Preserving secondary peptide structure

Details Preserving secondary peptide structure Preserving secondary peptide structure

A - Human Necessities

61

K

A61K 47/26 (2006.01) C07K 1/00 (2006.01)

Patent

CA 2692698

A method of preserving the a-helix secondary structure of N-Acetyl-D-Asp-D-Trp- D-Phe-D-Lys-D-Ala-D-Phe-D- Tyr-D-Asp-D-Lys-D-Val-D-Ala-D-Glu-D-Lys-D-Phe-D-Lys-D-Glu-D-Ala-D-Phe-Amide or N-Acetyl-L-Asp-L-Trp-L-Phe-L- Lys-L-Ala-L-Phe-L-Tyr-L-Asp-L-Lys-L-Val-L-Ala-L-Glu-L-Lys-L-Phe-L-Lys-L-Glu-L- Ala-L-Phe-Amide and compositions comprising such peptides are disclosed.

L'invention concerne des procédés de conservation de la structure secondaire de l'hélice a de N-acétyl-D-Asp-D-Trp-D-Phe-D-Lys-D-Ala-D-Phe-D-Tyr-D-Asp-D-Lys-D-Val-D-Ala-D-Glu-D-Lys-D-Phe-D-Lys-D-Glu-D-Ala-D-Phe-amide ou N-acétyl-L-Asp-L-Trp-L-Phe-L-Lys-L-Ala-L-Phe-L-Tyr-L-Asp-L-Lys-L-Val-L-Ala-L-Glu-L-Lys-L-Phe-L-Lys-L-Glu-L-Ala-L-Phe-amide et des compositions comprenant de tels peptides.

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