C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2433802
The present invention provides purified secretory polynucleotides (sptm). Also encompassed are the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing sptm for the expression of SPTM. The invention additionally provides for the use of isolated and purified SPTM to induce antibodies and to screen libraries of compounds and the use of anti-SPTM antibodies in diagnostic assays. Also provided are microarrays containing sptm and methods of use.
L'invention concerne des polynucléotides sécrétrices purifiées (sptm). L'invention concerne également des polypeptides (SPTM) codés par les sptm. L'invention regarde l'utilisation des sptm ou de compléments, d'oligonucléotides ou de fragments de ceux-ci dans des dosages biologiques de diagnostic. L'invention concerne également des vecteurs et des cellules hôtes contenant des sptm pour l'expression des SPTM. L'invention décrit aussi l'utilisation de SPTM purifiés et isolés afin de produire des anticorps et de dépister des bibliothèques de composants et l'utilisation d'anticorps anti-SPTM dans des dosages biologiques de diagnostic. L'invention concerne enfin des jeux ordonnés d'échantillons contenant des sptm et des procédés d'utilisation.
Altus Christina M.
Chang Simon C.
Chen Alice J.
Daffo Abel
Dam Tam C.
Altus Christina M.
Chang Simon C.
Chen Alice J.
Daffo Abel
Dam Tam C.
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