Synthetic human neutralizing monoclonal antibodies to human...

Details Synthetic human neutralizing monoclonal antibodies to human... Synthetic human neutralizing monoclonal antibodies to human...

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/42 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 16/10 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2174532

The present invention describes synthetic human monoclonal antibodies that immunoreact with and neutralize human immunodefi- ciency virus (HIV). The synthetic monoclonal antibodies of this invention exhibit enhanced binding affinity and neutralization ability to gp 120. Also disclosed are immunotherapeutic and diagnostic methods of using the monoclonal antibodies, as well as cell lines for producing the monoclonal antibodies.

La présente invention se rapporte à des anticorps monoclonaux humains synthétiques présentant une immunoréaction avec le virus de l'immunodéficience humaine (VHI) et neutralisant ce dernier. Les anticorps monoclonaux synthétiques selon l'invention présentent une affinité de liaison et une aptitude de neutralisation améliorée de la glycoprotéine gp120. L'invention se rapporte également à des procédés immunothérapeutiques et diagnostiques consistant à utiliser ces anticorps, ainsi qu'à des lignées cellulaires permettant de produire ces derniers.

Affiliated with

Also associated with

Rating

Synthetic human neutralizing monoclonal antibodies to human... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthetic human neutralizing monoclonal antibodies to human..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthetic human neutralizing monoclonal antibodies to human... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1430578