Pyrazoloquinoline derivatives

Details Pyrazoloquinoline derivatives Pyrazoloquinoline derivatives

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2051310

A pyrazoloquinoline derivative having the formula (I): Image (I) wherein R1, R2, and R3 independently represent a hydrogen atom or a lower alkyl group; R4 represents a hydrogen atom, a lower alkyl group, a halogen-substituted lower alkyl group, or a lower alkoxycarbonyl group; the dotted line means that the pyrazole ring has two conjugated double bonds; and R4 is bonded to the nitrogen atom at the 1-position or 2-position, or pharmacologically acceptable salts thereof. These compounds exhibit excellent anti-inflammatory activity and hepatic insufficiency treating activity.

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