Cobalamin conjugates useful as antitumor agents

A - Human Necessities – 61 – K

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A61K 41/00 (2006.01)

Patent

CA 2370419

The invention provides cobalamin compounds linked to a neutron capture therapy target (e.g. Boron-10 or Gadolinium-157), and optionally linked to a detectable moiety, as well as pharmaceutical compositions comprising the compounds, and methods for using the compounds in medical diagnosis and therapy.

L'invention concerne des composés de cobalamine liés à une cible thérapeutique de capture de neutrons (Bore-10 ou Gadolinium-157), et éventuellement liés à une fraction décelable, ainsi que des compositions pharmaceutiques comprenant lesdits composés, et des méthodes d'utilisation de ces composés dans le diagnostic et les thérapies médicales.

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