A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/215 (2006.01) A61K 31/336 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2731171
The present invention re-lates to methods of activate an isoform of protein kinase C (PKC) for the treatment of neurological diseases including Alzheimer's disease and stroke using cy-clopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids The present invention also relates to methods of reducing neurodegenera-tion using cyclopropanated or epoxi-dized derivatives of mono- and polyun-saturated fatty acids
L'invention concerne des procédés visant à activer un isoforme de la protéine kinase C (PKC) utile dans le traitement de maladies neurologiques, y compris la maladie d'Alzheimer et l'accident vasculaire cérébral, au moyen de dérivés cyclopropanés ou époxydés d'acides gras monoinsaturés et polyinsaturés. L'invention concerne aussi des procédés visant à réduire la neurodégénérescence à l'aide de dérivés cyclopropanés ou époxydés d'acides gras monoinsaturés et polyinsaturés.
Alkon Daniel L.
Nelson Thomas J.
Blanchette Rockefeller Neurosciences Institute
Gowling Lafleur Henderson Llp
LandOfFree
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