Bile acid-substituted phenyl-alkenoylguanidines, method for...

C - Chemistry – Metallurgy – 07 – C

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C07C 279/24 (2006.01) A61K 31/575 (2006.01) A61P 1/16 (2006.01) C07J 9/00 (2006.01) C07J 41/00 (2006.01)

Patent

CA 2383729

The invention relates to substituted acylguanidines and their pharmaceutically compatible salts and physiologically functional derivatives. The invention also relates to compounds of formula (I), wherein the radicals have the meanings given and to their physiologically compatible salts, their physiologically functional derivatives and methods for producing them. The inventive compounds are suitable for use e.g., as medicaments for preventing or treating bile stones.

L'invention concerne de la guanidine acylée substituée, ses sels pharmaceutiquement tolérables et ses dérivés physiologiquement fonctionnels. L'invention concerne également les composés de la formule (I), où les restes ont la signification donnée, ainsi que leurs sels physiologiquement compatibles, leurs dérivés physiologiquement fonctionnels et leurs procédés de production. Ces composés sont adaptés, par exemple, comme médicaments pour prévenir et traiter des calculs biliaires.

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