Expandable medical device with openings for delivery of...

A - Human Necessities – 61 – F

Patent

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A61F 2/06 (2006.01) A61L 31/14 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2499594

An expandable medical device includes a plurality of elongated struts, forming a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter. A plurality of different beneficial agents can be loaded into different openings (30a, 30b) within the struts for delivery to the tissue. For treatment of specified conditions such as edge effect restenosis or for improved spacial distribution of the delivered beneficial agent, different beneficial agents are loaded into different openings in the device in a predefined pattern. The different beneficial agents may include one or more different drugs, the same drugs in different concentrations or with different erosion rates, or different forms of the same drug.

L'invention concerne un dispositif médical extensible qui comprend une pluralité d'entretoises allongées formant un dispositif pratiquement cylindrique, extensible d'un cylindre ayant un premier diamètre à un cylindre ayant un deuxième diamètre. Une pluralité d'agents bénéfiques différents peut être chargée dans différentes ouvertures à l'intérieur des entretoises afin d'être administrée aux tissus. Pour traiter des affections spécifiques, telles que la resténose à effet de bord, ou pour améliorer la distribution spatiale de l'agent bénéfique administré, différents agents bénéfiques sont chargés dans différentes ouvertures du dispositif selon un motif prédéfini. Les différents agents bénéfiques peuvent inclure un ou plusieurs médicaments différents, les mêmes médicaments dans différentes concentrations ou avec différents taux d'érosion ou bien différentes formes du même médicament.

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