Novel bis-amides as antimalarial agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/16 (2006.01) A61K 31/165 (2006.01) A61K 31/435 (2006.01) C07C 237/06 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2742903

The invention relates to novel bis-amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria.

La présente invention décrit de nouveaux dérivés de bisamide ainsi que leur emploi en tant que principes actifs dans l'élaboration de compositions pharmaceutiques. La présente invention concerne également des aspects apparentés, y compris les compositions pharmaceutiques contenant un ou plusieurs de ces composés et leur emploi en tant que médicament dans le traitement prophylactique ou thérapeutique d'infections à protozoaires, par exemple, spécialement, le paludisme.

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