Combined approach to treatment of cancer with hcg vaccines

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/26 (2006.01) A61K 38/24 (2006.01) A61K 39/395 (2006.01) C07K 16/30 (2006.01) G01N 33/76 (2006.01)

Patent

CA 2369397

The invention relates to an improved method for immunotherapy of cancer by administering to a subject a human anti-hCG monoclonal antibody and/or an hCG immunogenic peptide vaccine, followed by monitoring the patient's immune response to hCG-CTP16, hCG-CTP21 and hCG-CTP37, respectively, and adjusting the vaccination regimen according to the detectable immune response to the hCG immunogenic peptides. The invention further relates to devices, methods and kits for immunoassay of hCG immunogenic peptides.

L'invention concerne une méthode améliorée d'immunothérapie du cancer selon laquelle on administre à un individu un anticorps monoclonal anti-hCG et/ou un vaccin à base de peptides immunogènes hCG, puis on surveille la réponse immunitaire du patient à hCG-CTP16, hCG-CTP21 et à hCG-CTP37 respectivement, pour ensuite adapter le schéma posologique de vaccination selon la réponse immunitaire aux peptides immunogènes hCG détectable. L'invention concerne également des dispositifs, des méthodes et des kits de dosages immunologiques de peptides immunogènes hCG.

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