Streptococcus uberis adhesion molecule

Details Streptococcus uberis adhesion molecule Streptococcus uberis adhesion molecule

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) C07K 14/315 (2006.01) C07K 16/12 (2006.01) C12N 15/74 (2006.01)

Patent

CA 2507163

A polypeptide, designated as ~Streptococcus uberis Adhesion Molecule~ (SUAM), and fragments of SUAM, prevent internalization and adherence of Streptococcus uberis and other streptococcal pathogens to cells. The SUAN polypeptide and fragments may be used diagnostically and therapeutically. Nucleic acid sequences encoding the SUAM polypeptide and fragments are included in the invention.

L'invention concerne un polypeptide, désigné sous l'appellation de molécule d'adhésion de Streptococcus uberis, et des fragments dudit polypeptide, qui empêchent l'internalisation de Streptococcus uberis et d'autres pathogènes streptococciques et l'adhérence de Streptococcus uberis et d'autres pathogènes streptococciques aux cellules. Ledit polypeptide et ses fragments peuvent être employés à des fins diagnostiques et thérapeutiques. L'invention concerne également des séquences d'acides nucléiques codant ledit polypeptide et ses fragments.

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