Novel compounds and compositions as protein kinase inhibitors

Details Novel compounds and compositions as protein kinase inhibitors Novel compounds and compositions as protein kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/02 (2006.01) A61K 31/505 (2006.01) A61K 31/513 (2006.01) A61K 31/53 (2006.01) A61P 29/00 (2006.01) C07D 239/02 (2006.01) C07D 251/18 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2521184

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated tyrosine kinase activity, particularly diseases associated with the activity of PDGF-R, c-Kit and Bcr-abl.

L'invention concerne une nouvelle classe de composés, des compositions pharmaceutiques contenant lesdits composés, et des méthodes d'utilisation de ces composés dans le traitement ou la prévention des maladies ou des troubles associés à une activité anormale ou déréglée de la tyrosine kinase, en particulier les maladies associées à l'activité de PDGF-R, c-Kit et Bcr-abl.

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