Benzoxazines for use in the treatment of parkinson's disease

Details Benzoxazines for use in the treatment of parkinson's disease Benzoxazines for use in the treatment of parkinson's disease

C - Chemistry, Metallurgy

07

D

C07D 498/14 (2006.01) A61K 31/5365 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2407789

Benzoxazines of Formula (I) wherein R1 is C1-C6 alkyl, C2-C6 alkenyl, or (CH2)nphenyl, R2 is C3-C6 alkyl, R3 is hydrogen, halo, hydroxy, alkoxy, or alkylthio, R4 is hydrogen or alkyl, or a pharmaceutically acceptable salt thereof, are useful for treating movement disorders such as Parkinson's disease.

L'invention concerne des benzoxazines de la formule I, dans laquelle R?1¿ représente C¿1?-C¿6?alkyle, C¿2?-C¿6?alcényle, ou (CH¿2?)¿n?phényle; R?2¿ représente C¿3?-C¿6?alkyle, R?3¿ représente hydrogène, halo, hydroxy, alcoxy, ou alkylthio; R?4¿ représente hydrogène ou alkyle, ou un de leurs sels pharmaceutiquement acceptables, qui permettent de traiter des troubles de la motricité, tels que la maladie de Parkinson.

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