Attenuated revertant serotype 1 marek's disease vaccine

Details Attenuated revertant serotype 1 marek's disease vaccine Attenuated revertant serotype 1 marek's disease vaccine

A - Human Necessities

61

K

A61K 39/255 (2006.01) C07K 14/055 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2112225

A Marek's disease vaccine comprising an attenuated revertant virus derived as a clone of Mdll/75/R2 or an antigenic component of the virus is characterized by a markedly reduced pathogenicity compared to the parent virus, without a comparable loss in immunogenicity. Attenuated revertants of the invention are exemplified by Mdll/75/R2/23 and Mdll/75/R2/29. These viruses or immunogenic components thereof can be formulated into monovalent and polyvalent vaccines.

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