In vivo insect model system for type-2 diabetes

C - Chemistry – Metallurgy – 12 – N

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C12N 15/00 (2006.01) A01K 67/033 (2006.01) C07K 14/435 (2006.01)

Patent

CA 2375484

An in vivo monitory system for e.g. investigating defects in the insulin signaling pathway and screening for drugs suitable for the treatment of such defects, in particular a system using Drosophila chico mutants, is disclosed as well as a method for using such a system and for its generation.

L'invention concerne un système d'observation in vivo permettant par exemple l'investigation des défauts de la voie de signalisation de l'insuline et l'identification de médicaments convenant pour le traitement de ces défaillances. L'invention concerne en particulier un système faisant appel à des drosophiles à mutation chico ainsi que l'utilisation et la production d'un tel système.

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