Peptides and peptide mimetics to treat pathologies...

Details Peptides and peptide mimetics to treat pathologies... Peptides and peptide mimetics to treat pathologies...

A - Human Necessities

61

K

A61K 38/00 (2006.01)

Patent

CA 2607483

This invention provides novel active agents (e.g. peptides, small organic molecules, amino acid pairs, etc.) peptides that ameliorate one or more symptoms of atherosclerosis and/or other pathologies characterized by an inflammatory response. In certain embodiment, the peptides resemble a G* amphipathic helix of apolipoprotein J. The agents are highly stable and readily administered via an oral route.

L'invention concerne de nouveaux agents actifs (tels que peptides, petites molécules organiques, paires d'acides aminés, etc.) qui sont des peptides améliorant un ou plusieurs symptômes de l'athérosclérose et/ou d'autres pathologies caractérisées par une réaction inflammatoire. Dans un mode de réalisation, les peptides ressemblent à l'hélice G* amphipathique de l'apolipoprotéine J. Les agents sont hautement stables et peuvent facilement être administrés par voie orale.

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