Stable aqueous g-csf formulations

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/19 (2006.01) A61K 9/08 (2006.01) A61K 9/12 (2006.01) A61K 31/56 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2679551

The invention relates to stable glutamate-buffered G-CSF formulations having a pH of from 3.5 to 4.8. The invention further concerns lyophilisates and powders obtainable from such formulations, and to pharmaceutical kits containing such lyophilisates and powders.

La présente invention concerne des formulations stables de G-CSF tamponnées avec du glutamate, présentant un pH compris entre 3,5 et 4,8. L'invention concerne en outre des lyophilisats et des poudres pouvant être obtenues à partir de ces formulations, ainsi que des kits pharmaceutiques contenant de tels lyophilisats et de telles poudres.

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