Methods and compositions useful for inhibition of angiogenesis

Details Methods and compositions useful for inhibition of angiogenesis Methods and compositions useful for inhibition of angiogenesis

A - Human Necessities

61

K

A61K 38/48 (2006.01) A61K 31/195 (2006.01) A61K 31/22 (2006.01) A61K 31/27 (2006.01) A61K 31/42 (2006.01) A61K 38/04 (2006.01) A61K 38/12 (2006.01) A61K 38/16 (2006.01) A61K 38/36 (2006.01) A61K 38/39 (2006.01) A61K 39/395 (2006.01) C07C 279/14 (2006.01) C07C 311/06 (2006.01) C07C 311/10 (2006.01) C07D 263/38 (2006.01) C07K 14/75 (2006.01) C07K 16/28 (2006.01) C12N 9/64 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2256543

The present invention describes methods for inhibition of angiogenesis in tissues using vitronectin .alpha.v.beta.3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic compositions containing .alpha.v.beta.3 antagonists.

L'invention concerne des procédés capables d'inhiber l'angiogenèse dans les tissus, par le biais d'antagonistes des récepteurs .alpha.¿v?.beta.¿3? de vitronectine, notamment pour inhiber l'angiogenèse dans les tissus enflammés et tumoraux ou les métastases à l'aide de compositions thérapeutiques renfermant lesdits antagonistes.

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