Glucuronoxylomannan (gxm)-o-acetylhydrolase of cryptococcus...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 9/18 (2006.01) C12N 15/55 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2381607

The present invention provides a novel enzyme which de-O-acetylates glucuronoxylomannan of Cryptococcus neoformans and a gene encoding such enzyme. Also provided are applications of such enzyme in treating cryptococcosis.

La présente invention concerne, d'une part une nouvelle enzyme qui dés-O-acétylise le glucuronoxylomannane de Cryptococcus neoformans et d'autre part un gène codant une telle enzyme. L'invention concerne également des applications d'une telle enzyme pour le traitement de la cryptococcose.

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