Novel compositions and methods in cancer

Details Novel compositions and methods in cancer Novel compositions and methods in cancer

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 14/82 (2006.01) C07K 16/32 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2513137

The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is dys-regulated in cancer tissues. The present invention provides CA polypeptides associated with cancer and provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

La présente invention concerne de nouvelles séquences utilisées pour la détection, le diagnostic et le traitement de cancers, notamment de lymphomes. L'invention a aussi pour objet : des séquences polynucléotidiques associées au cancer (AC) dont l'expression est mal régulée dans les tissus cancéreux ; des polypeptides AC associés au cancer et des compositions diagnostiques et des procédés de détection du cancer ; des anticorps monoclonaux et polyclonaux spécifiques des polypeptides CA ; des outils diagnostiques et des compositions thérapeutiques et des procédés de criblage, de prévention et de traitement du cancer.

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