Gene involved in epigenetic gene silencing

Details Gene involved in epigenetic gene silencing Gene involved in epigenetic gene silencing

C - Chemistry, Metallurgy

12

N

C12N 15/29 (2006.01) C07K 14/415 (2006.01) C12N 15/82 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2369749

The present invention relates to DNA which encodes proteins involved in gene silencing. Related genes encoding proteins characterized by an amino acid sequence comprising a component sequence of at least 150 amino acid residues having 40% or more identity with an alinged component sequence of SEQ ID NO:3 can be isolated from different sources such as mammalian or plant cells. Further disclosed is a method for isolating DNA according to the invention.

La présente invention concerne un ADN codant pour des protéines impliquées dans l'inhibition d'un gène. Ces gènes codant pour des protéines caractérisées par une séquence d'acide aminé comprenant une séquence de composants constituée d'au moins 150 restes d'acide aminé présentant une similitude supérieure à 40 % avec une séquence de composants alignée SEQ ID NO:3, peuvent être isolés de différentes sources telles que les cellules mammifères ou les cellules végétales. L'invention concerne également un procédé permettant d'isoler de l'ADN.

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