N-(aroyl)glycine hydroxamic acid derivatives and related...

Details N-(aroyl)glycine hydroxamic acid derivatives and related... N-(aroyl)glycine hydroxamic acid derivatives and related...

C - Chemistry, Metallurgy

07

C

C07C 259/06 (2006.01) A61K 31/165 (2006.01) A61K 31/166 (2006.01) A61K 31/195 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/401 (2006.01) A61K 31/445 (2006.01) C07C 235/52 (2006.01) C07C 323/59 (2006.01) C07D 205/04 (2006.01) C07D 207/08 (2006.01) C07D 207/16 (2006.01) C07D 211/60 (2006.01)

Patent

CA 2227237

Compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, AA and Y are as defined herein, inhibit phosphodiesterase type IV or inhibit the production of tumor necrosis factor, and therefore are useful in the treatment of certain conditions and diseases including asthma, arthritis, and sepsis.

La présente invention concerne des composés représentés par la formule (I) et des sels de ces composés acceptables en pharmacie. R<1>, R<2>, AA et Y sont tels que les définit la description. Ces différents composés inhibent la phosphodiestérase du type IV ou la production du facteur de nécrose des tumeurs, et ils sont donc utiles dans le traitement de certains états et maladies, y compris l'asthme, l'arthrite et la septicémie.

Affiliated with

Also associated with

Rating

N-(aroyl)glycine hydroxamic acid derivatives and related... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-(aroyl)glycine hydroxamic acid derivatives and related..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-(aroyl)glycine hydroxamic acid derivatives and related... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1437638