Hepatitis c virus protease

Details Hepatitis c virus protease Hepatitis c virus protease

C - Chemistry, Metallurgy

12

N

C12N 15/57 (2006.01) C07K 14/00 (2006.01) C12N 9/02 (2006.01) C12N 9/50 (2006.01) C12N 15/62 (2006.01) C12Q 1/37 (2006.01) C12Q 1/70 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2079105

The protease necessary for polyprotein processing in Hepatitis C virus is identified, cloned, and expressed. Proteases, truncated protease, and altered proteases are disclosed which are useful for cleavage of specific polypeptides, and for assay and design of antiviral agents specific for HCV.

On identifie, on clone et on exprime la protéase nécessaire au traitement polyprotéique dans le virus de l'hépatite C. On décrit des protéases, des protéases tronquées et des protéases modifiées utiles au clivage de polypeptides spécifiques, ainsi qu'à l'analyse et à la conception d'agents antiviraux spécifiques au virus de l'hépatite C.

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