Use of piperazine sulfonic acid derivatives as ccr1...

Details Use of piperazine sulfonic acid derivatives as ccr1... Use of piperazine sulfonic acid derivatives as ccr1...

A - Human Necessities

61

K

A61K 31/495 (2006.01) A61P 25/00 (2006.01) A61P 25/18 (2006.01) A61P 29/00 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2500850

The present invention relates to methods of using CCR1 antagonists as immunomodulatory agents. In particular, the methods relate to using compounds of the formula (I) or the pharmaceutically acceptable salt thereof; wherein X, Y, a, b, c, d, R1, R2, R3 and R5 are as defined herein.

La présente invention concerne des procédés d'utilisation d'antagonistes CCR1 en tant qu'agents immunomodulateurs. Notamment, les procédés utilisent des composés de la formule (I) ou le sel correspondant acceptable pharmaceutiquement, X, Y, a, b, c, d, R?1¿, R?2¿, R?3¿ et R?5¿ étant tels que définis dans l'invention.

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