Cryptosporidium parvum antigens, antibodies thereto and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/30 (2006.01) A61K 39/002 (2006.01) A61K 39/395 (2006.01) C07K 14/44 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2411949

Cloning and expression of genes encoding C. parvum antigenic polypeptides are described as are antibodies that recognize epitopes on these polypeptides. The antigenic polypeptides and antibodies thereto can be used in therapeutic compositions for the prevention and treatment of C. parvum infections, as well as in diagnostic methods for determining the presence of C.parvum infections.

L'invention concerne le clonage et l'expression de gènes codant les polypeptides antigéniques de <i> C. parvum</i>, ainsi que des anticorps reconnaissant les épitopes présents sur ces polypeptides. Lesdits polypeptides antigéniques et leurs anticorps peuvent être utilisés soit dans des compositions thérapeutiques destinées à la prévention et au traitement des infections au <i>C. parvum</i>, soit dans des méthodes diagnostiques de détermination de la présence d'infections au <i>C.parvum</i>.

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