Purification of fermented clavulanic acid

Details Purification of fermented clavulanic acid Purification of fermented clavulanic acid

C - Chemistry, Metallurgy

07

D

C07D 503/02 (2006.01) C07D 503/00 (2006.01)

Patent

CA 2273021

A process for the production of clavulanic acid and pharmaceutically acceptable salts thereof by: a) fermentation of a micro-organism which is capable to produce clavulanic acid, b) isolation of clavulanic acid from the fermentation broth, c) purification of clavulanic acid, e.g. via a salt thereof, d) conversion of the purified clavulanic acid of step c), e.g. of a salt thereof into a pharmaceutically acceptable salt of clavulanic acid, wherein the fermentation broth is extracted with a solvent prior to isolation of clavulanic acid.

Cette invention porte sur un procédé de production d'acide clavulanique et de sels pharmaceutiquement acceptables dudit acide. Le procédé consiste a) à faire fermenter un micro-organisme capable de produire de l'acide clavulanique; b) à isoler l'acide clavulanique du bouillon de fermentation; c) à purifier l'acide clavulanique, par exemple au moyen d'un sel dudit acide; d) à transformer l'acide clavulanique purifié de l'étape c), ou un sel dudit acide, en un sel pharmaceutiquement acceptable d'acide clavulanique. Le bouillon de fermentation est retiré à l'aide d'un solvant préalablement à l'isolation de l'acide clavulanique.

Affiliated with

Also associated with

Rating

Purification of fermented clavulanic acid does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Purification of fermented clavulanic acid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purification of fermented clavulanic acid will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1439514