Immunogen adherence inhibitor and method of making and using...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A23J 3/12 (2006.01) A23K 1/16 (2006.01) C07K 16/12 (2006.01)

Patent

CA 2438698

A microbial adherence inhibitor in the form of fowl egg antibodies is disclosed, along with the method of making it and methods of using it. The inhibitor functions by substantially preventing the attachment or adherence of colony-forming immunogens in the rumen and intestinal tracts of host food animals. The inhibitor is made by inoculating female birds with the immunogen, harvesting the eggs which contain antibodies to the immunogen, drying the egg contents and adding to the feed or water for the host animals. Dependent upon the particular immunogen with which the female bird is inoculated, the egg antibody is used to promote the growth of food animals by improving feed conversion rates by decreasing the waste of dietary protein caused by the presence of certain colony-forming organisms in the animals, and to substantially reduce or eliminate the incidence of illnesses caused by the presence of certain illness-causing colony-forming immunogens, such as E. coli 0157:H7), in meat from food animals, and in other food stuffs.

L'invention concerne un inhibiteur de l'adhérence microbienne sous la forme d'anticorps d'oeufs de volaille, ainsi que sa méthode d'élaboration et ses méthodes d'utilisation. L'action de cet inhibiteur repose sur la prévention quasi-totale de l'attachement ou de l'adhérence d'immunogènes formant des colonies dans la panse ou les tractus intestinaux d'animaux hôtes destinés à la consommation. On élabore ledit inhibiteur en inoculant des oiseaux femelles avec l'immunogène, en recueillant les oeufs qui renferment des anticorps contre l'immunogène, en séchant les contenus des oeufs et en les ajoutant aux aliments ou à l'eau des animaux hôtes. En fonction de l'immunogène spécifique avec lequel on inocule l'oiseau femelle, on utilise l'anticorps de l'oeuf pour aider la croissance des animaux destinés à la consommation, en améliorant les taux de conversion alimentaire, en diminuant le gaspillage de protéines alimentaires occasionné par la présence de certains organismes formant des colonies chez des animaux, et pour réduire ou éliminer pratiquement l'incidence de maladies provoquées par la présence de certains immunogènes formant des colonies, occasionnant des maladies, tels que <u>E. coli 0157:H7)</u>, dans la viande provenant d'animaux destinés à la consommation et dans d'autres denrées alimentaires.

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