Use of multi-specific, non-covalent complexes for targeted...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61K 33/00 (2006.01) A61K 45/06 (2006.01) A61K 47/48 (2006.01) A61K 51/04 (2006.01) A61K 51/08 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) C07K 16/44 (2006.01)

Patent

CA 2505717

The invention relates to a method for treating target cells, tissues or pathogens in a subject, comprising administering a non-covalently bound complex which comprises a multispecific targeting protein and a hapten-enzyme covalent conjugate. The invention further relates to kits comprising the non- covalently bound complex or the components to prepare the complex.

L'invention porte sur un procédé de traitement de cellules, tissus ou agents pathogènes cibles chez un sujet, ce procédé consistant à administrer un complexe lié de manière non covalente qui comprend une protéine de ciblage à multi-spécificité et un conjugué covalent haptène-enzyme. L'invention porte également sur des kits comprenant le complexe lié de manière non covalente ou les composants pour préparer le complexe.

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