Indole derivatives with affinity for the cannabinoid receptor

Details Indole derivatives with affinity for the cannabinoid receptor Indole derivatives with affinity for the cannabinoid receptor

C - Chemistry, Metallurgy

07

D

C07D 209/10 (2006.01) A61K 31/40 (2006.01) A61K 31/425 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 209/14 (2006.01) C07D 209/26 (2006.01) C07D 405/02 (2006.01) C07D 409/02 (2006.01) C07D 417/02 (2006.01)

Patent

CA 2211836

Disclosed are indole derivatives of formula (I) having activity on the cannabinoid receptors and the methods of their preparation. The compounds are useful for lowering ocular intraocular pressure and treating glaucoma because of the activity of the cannabinoid receptor.

La présente invention concerne des dérivés d'indole ayant la formule (I) et qui ont une activité sur les récepteurs cannabinoïdes. L'invention concerne aussi les procédés de préparation de ces dérivés. Ces composés sont utiles pour abaisser la pression oculaire intra-oculaire et pour traiter le glaucome en raison de l'activité du récepteur cannabinoïde.

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