Methods for noninvasively measuring analyte levels in a subject

Details Methods for noninvasively measuring analyte levels in a subject Methods for noninvasively measuring analyte levels in a subject

A - Human Necessities

61

B

A61B 5/1495 (2006.01) A61B 5/1455 (2006.01)

Patent

CA 2610249

A method for noninvasively measuring analytes such as blood glucose levels includes using a non-imaging OCT-based system to scan a two-dimensional area of biological tissue and gather data continuously during the scanning. Structures within the tissue where measured-analyte-induced changes to the OCT data dominate over changes induced by other analytes are identified by focusing on highly localized regions of the data curve produced from the OCT scan which correspond to discontinuities in the OCT data curve. The data from these localized regions then can be related to measured analyte levels.

L'invention concerne un procédé permettant de mesurer de manière non invasive des analytes, par exemple les niveaux de glucose dans le sang, qui consiste notamment à utiliser un système fondé sur une tomographie de cohérence optique (OCT) pour explorer une zone bidimensionnelle d'un tissu biologique et recueillir en continu des données durant le balayage. Des structures dans le tissu où des changements mesurés induits par l'analyte aux données OCT dominent par rapport à des changements induits par d'autres analytes, sont identifiées par focalisation sur des régions très localisées de la courbe de données produite par le balayage OCT qui correspondent à des discontinuités dans la courbe de données OCT. On peut alors rapporter les données de ces régions localisées à des niveaux d'analyte mesurés.

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