Method for selectively depleting hypoxic cells

Details Method for selectively depleting hypoxic cells Method for selectively depleting hypoxic cells

C - Chemistry, Metallurgy

12

N

C12N 5/06 (2006.01)

Patent

CA 2624707

An improved method for selectively depleting hypoxic cells within the bone marrow is disclosed. The method can be used to enhance engraftment of hematopoietic stem cells (HSCs) in the bone marrow of a host subject. Also disclosed is a method for treating a cancer within the bone marrow of a host subject.

L'invention concerne une méthode améliorée de déplétion sélective de cellules hypoxiques dans la moelle osseuse. La méthode peut être utilisée pour améliorer la prise de greffe de cellules souches hématopoïétiques (HSC) dans la moelle osseuse d'un sujet hôte. L'invention concerne en outre une méthode de traitement d'un cancer de la moelle osseuse d'un sujet hôte.

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