C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/48 (2006.01) A61K 31/4709 (2006.01) A61P 25/18 (2006.01)
Patent
CA 2672920
This invention provides novel aryl piperazine derivatives represented by Formula (I) having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D3, 5HT1A and 5-HT2A receptor subtypes, and in particular useful for the treatment of neuropsychiatric disorders, incl. schizophrenia.
La présente invention concerne de nouveaux dérivés d'arylpipérazine qui répondent à la Formule (I) et présentent une utilité médicale, particulièrement en tant que modulateurs de la dopamine et récepteurs de la sérotonine, de préférence les sous-types de récepteurs D3, 5HT1A et 5-HT2A. Les dérivés se révèlent particulièrement utiles pour le traitement de troubles neuropsychiatriques, notamment la schizophrénie.
Butini Stefania
Campiani Giuseppe
Fattorusso Caterina
Franceschini Silvia
Irene Thale Zia
Mccarthy Tetrault Llp
Universita'degli Studi Di Siena
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