C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/444 (2006.01) A61P 11/00 (2006.01) A61P 11/08 (2006.01)
Patent
CA 2758505
This invention relates to a compound of formula I; or a pharmaceutically acceptable salt thereof. Such compounds possess both muscarinic receptor antagonist and .beta.2 adrenergic receptor agonist activities. The invention also relates to pharmaceu-tical compositions comprising such compounds, processes and intermediates for preparing such compounds, and methods of using such compounds as bronchodilating agents to treat pulmonary disorders.
L'invention concerne un composé de formule I; ou un sel de celui-ci pharmaceutiquement acceptable. Ces composés possèdent les activités aussi bien de l'antagoniste du récepteur muscarinique que de l'agoniste des récepteurs adrénergiques bêta2. L'invention concerne également des compositions pharmaceutiques comprenant ces composés, des processus et des intermédiaires pour la préparation de ces composés; elle concerne en outre des procédés d'utilisation de ces composés comme agents bronchodilatateurs pour le traitement de troubles pulmonaires.
Byun Daniel
Chen Yan
Fleury Melissa
Hughes Adam
Jacobsen John R.
Theravance Inc.
Torys Llp
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