Method for separating glycolipids from a lipid mixture and...

C - Chemistry – Metallurgy – 07 – F

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167/199, 260/229

C07F 9/10 (2006.01) A23J 7/00 (2006.01) A61K 8/14 (2006.01) A61K 8/55 (2006.01) A61K 8/68 (2006.01) A61K 8/98 (2006.01) A61K 9/127 (2006.01) A61K 31/00 (2006.01) A61K 31/685 (2006.01) A61Q 19/00 (2006.01) C07H 15/04 (2006.01)

Patent

CA 2000657

Abstract A method for separating glycolipids from a lipid mixture and uses of the fractions obtained To separate the glycolipids from a lipid mixture containing complex lipids, the neutral lipids are optional- ly separated therefrom by chromatography on silica gel, after which the glycolipids are separated from the phospho- lipids by chromatography on boric acid gel. The ganglio- sides may then optionally be separated from the fraction containing the glycolipids by a solvent in the presence of water. The fraction containing the glycolipids may be treated by ion exchange chromatography to separate the non- acidic glycolipids from the acidic glycolipids. Similarly, the non-acidic phospholipids and the acidic phospholipids may be separated by ion exchange chromatography from the fraction containing the phospholipids. The various fractions may be incorporated in dietetic products, particularly for infants, cosmetic products or pharmaceutical products.

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