C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) C07K 1/30 (2006.01) C07K 1/36 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2673851
Methods are presented for isolating and purifying antibodies by adding a polyelectrolyte to a cell culture fluid, such as a harvested cell culture fluid, and precipitating an antibody-polyelectrolyte complex or a complex of impurities and the polyelectrolyte.
La présente invention concerne des procédés permettant d'isoler et de purifier des protéines par ajout d'un polyélectrolyte à un fluide de culture cellulaire, tel un fluide de culture de cellules récoltées, et par précipitation d'un complexe protéine-polyélectrolyte ou d'un complexe d'impuretés et du polyélectrolyte.
Fahrner Robert L.
Franklin Jayme
Mcdonald Paul J.
Peram Thanmaya
Sisodiya Vikram
Genentech Inc.
Smart & Biggar
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