Thf-containing sulfonamide inhibitors of aspartyl protease

Details Thf-containing sulfonamide inhibitors of aspartyl protease Thf-containing sulfonamide inhibitors of aspartyl protease

C - Chemistry, Metallurgy

07

D

C07D 307/18 (2006.01) A61K 31/33 (2006.01) C07D 209/08 (2006.01) C07D 213/30 (2006.01) C07D 215/48 (2006.01) C07D 231/14 (2006.01) C07D 239/22 (2006.01) C07D 263/24 (2006.01) C07D 271/08 (2006.01) C07D 277/36 (2006.01) C07D 307/12 (2006.01) C07D 307/20 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 407/00 (2006.01) C07D 409/00 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 411/00 (2006.01) C07D 413/00 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 41

Patent

CA 2217737

The present invention relates to a class of THF-containing sulfonamides which are aspartyl protease inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention.

La présente invention se rapporte à une classe de sulfamides contenant THF qui sont des inhibiteurs de la protéase aspartyle, ainsi qu'à des compositions pharmaceutiques comprenant ces composés. Les composés et compositions pharmaceutiques de cette invention sont notamment tout à fait appropriés pour inhiber l'activité de la protéase du VIH1 et du VIH2 et, par conséquent, peuvent être utilisés, pour plus d'efficacité, comme agents antiviraux contre le VIH1 et le VIH2. Cette invention se rapporte également à des procédés d'inhibition de l'activité de la protéase aspartyle du VIH qui mettent en oeuvre ces composés.

Affiliated with

Also associated with

Rating

Thf-containing sulfonamide inhibitors of aspartyl protease does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thf-containing sulfonamide inhibitors of aspartyl protease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thf-containing sulfonamide inhibitors of aspartyl protease will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1443625