Preparation of soluble n-protein/truncated p-protein...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/45 (2006.01) A61K 39/155 (2006.01) C07K 14/115 (2006.01) C07K 14/12 (2006.01) C07K 14/135 (2006.01)

Patent

CA 2606105

The invention relates to a method for preparation of soluble N-protein/truncated P-protein complex of a virus of the family Paramyxoviridae, complexes prepared thus and the soluble N-proteins which may be isolated from said complexes. The invention further relates to vaccine compositions comprising said N-protein/truncated P-protein complexes or N-proteins from Paramyxoviridae.

L'invention concerne un procédé de préparation d'un complexe soluble protéine N -protéine P tronquée d'un virus de la famille des Paramyxoviridae, les complexes ainsi préparés, ainsi que les protéines N solubles susceptibles d'être isolées à partir de ces complexes. L'invention concerne également des compositions vaccinales comprenant ces complexes protéine N -protéine P tronquée ou des protéines N de Paramyxoviridae.

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